ABSTRACT
Background: Sleep has a well-recognized impact on human immunity. COVID-19 infectivity and severity depend on the immune system of the host. Medical interns are at risk for the development of this disease and have poor sleep quality. In this study, the association between sleep quality and COVID-19 infection development and severity in medical students was evaluated. Methods: In the current study, 50 medical students were enrolled. Demographic and subjective sleep parameters were documented and compared with COVID-19 infection history and development of dyspnea. Chronotype was assessed by the reduced Morningness- Eveningness Questionnaire (rMEQ). Results: The total sleep time in infected medical intern were 68.14 minutes shorter than non-infected one (p=0.048). The wake time was one hour and twelve minutes earlier in the group which developed dyspnea (p=0.020). Age, gender, rMEQ score and Body Mass Index (BMI) are significantly associated with neither COVID-19 infection history nor dyspnea. Conclusion: Short sleep time and early morning awakening are bound up with the prevalence and severity of COVID-19 in medical interns. © 2022 by the Author(s).
ABSTRACT
Coronavirus infectious disease 2019 (COVID-19) is confirmed to develop neurocognitive complications. In the present paper, we describe two patients with laboratory-confirmed COVID-19 and excessive daytime sleepiness. In the present study, we reported two laboratory-confirmed cases of COVID-19 with excessive daytime sleepiness. Patients had drowsiness and mild confusion on presentation. In both cases, CNS infections, including meningitis and encephalitis, were ruled out. Both patients’ symptoms remarkably improved following the therapeutic course indicating the direct effect of SARS-CoV2 in sleep modulating centers on the brain. COVID-19 should be considered in patients with excessive daytime sleepiness and drowsiness in the current outbreak.
ABSTRACT
Background: Routine blood testing consists of Complete Blood Count (CBC) indices together with Comprehensive Metabolic Panel (CMP) which have significant roles in both diagnosis and prognosis of the novel coronavirus disease 2019 (COVID-19). Methods: A total number of 942 COVID-19 patients and 400 healthy persons as the control group were enrolled in this study. All patients were admitted to a single center and were divided into two groups according to disease severity (severe or non-severe). Routine laboratory findings of peripheral blood sample were collected and then analyzed. Results: Neutrophil-Lymphocyte Ratio (NLR) had the highest sensitivity and specificity value for COVID-19 diagnosis. Among patients with different severities of COVID-19, the amount of neutrophil, NLR, platelet, hemoglobin, Red cell Distribution Width (RDW) and total bilirubin was significantly different (p<0.01). Conclusion: Some indices of complete blood count and comprehensive metabolic panel have diagnostic and prognostic roles in COVID-19 patients, which are helpful in early diagnosis, predicting severity and adverse outcomes of patients with COVID-19. © 2021 Islamic Republic of Iran Medical Council. All Rights Reserved.
ABSTRACT
Objectives: Considering the reduction of patients' attendance in hospitals, including patients with nose fracture, in fear of COVID-19 transmission, this study aims to investigate the risk of nosocomial COVID-19 transmission in patients with nasal trauma seeking medical care in hospital. Methods: Patients with nasal trauma referred to our specialized ENT referral center were evaluated, treated, and followed, up to two weeks. After discharge, COVID-19 symptoms were questioned by telephone, and additional assessments were requested for suspected patients. Results: Out of 108 patients with possible nasal fracture, 27 didn't need nasal reduction after physical examination while 81 required nasal bone reduction. Only one of the patients contracted the virus in the 2-week follow-up period, and the difference between the two groups was not statistically significant. Conclusion: Patients in need of emergency medical services -like nasal trauma-in outpatient and short-term inpatient settings should not avoid going to the hospitals. This is provided when both medical staff and patients follow the health protocols.